Clearer Thinking with Spencer Greenberg cover image

Clearer Thinking with Spencer Greenberg

Could the placebo effect be bullshit? (with Literal Banana)

Jan 15, 2025
Literal Banana, a quirky banana who escaped a high-tech produce delivery, dives deep into the placebo effect and its implications for human psychology. She questions whether the placebo effect is just 'scientific-sounding woo' and discusses the importance of both placebo and no-treatment groups in research. Banana also examines the nuances between open-label and closed-label placebos and how belief can influence physical sensations. Join her on a journey to understand the complexities of mind-body connections and the role of mindset in wellness.
01:27:15

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • The podcast discusses the skepticism surrounding the placebo effect, suggesting that perceived improvements are often due to belief and expectation rather than actual healing properties.
  • The role of expectation and social dynamics in clinical trials is highlighted, indicating that external factors can artificially inflate reported responses to placebo treatments.

Deep dives

Skepticism Surrounding the Placebo Effect

The discussion begins with skepticism about the existence of the placebo effect, suggesting that while placebo-controlled trials are effective for study design, the alleged healing powers attributed to placebos may lack substantial scientific support. The distinction between a placebo group used in trials and the actual placebo effect is clarified, highlighting that many variables contribute to perceived improvements in conditions like depression. It’s argued that the improvements reported by those in placebo groups often stem from belief, expectation, or natural recovery rather than any intrinsic healing effect of the placebo itself. The speaker points out that ongoing research into how belief impacts physiological responses has not yielded broad, replicable evidence of a strong placebo effect.

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