Placebo interventions for all clinical conditions

This systematic review, published in the Cochrane Database of Systematic Reviews, evaluates the effectiveness of placebo interventions in improving patient-reported and observer-reported outcomes.

The authors analyzed data from numerous randomized trials comparing placebo with no treatment and found that, in general, placebo interventions did not have clinically significant effects on most clinical conditions.

The review highlights the importance of rigorous trial design and the need for evidence-based assessments of placebo effects.