Mayo Clinic Talks

Rheumatology Edition | When to Suspect (RA) Rheumatoid Arthritis

14 snips
Jan 25, 2024
In this podcast, rheumatologist Vanessa L. Kronzer discusses rheumatoid arthritis (RA), including its clinical manifestations, challenges in diagnosis, and effective treatment and management options. Topics covered include risk factors, atypical presentations, use of x-rays for diagnosis, and management with drugs like methotrexate and TNF inhibitors. They also explore achieving remission and burnt out RA.
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INSIGHT

Key Risk Factors And Demographics

  • Rheumatoid arthritis (RA) is more common in women and peaks in the 30s and again in the 50s–60s.
  • Smoking and obesity substantially increase RA risk, with smoking raising risk ~3-fold.
INSIGHT

Classic Versus Atypical Presentations

  • Classic RA affects symmetrical small joints like MCPs, PIPs, wrists and MTPs but many cases are atypical.
  • RA can present palindromically with episodic attacks that come and go like gout.
ADVICE

How To Differentiate RA From Other Arthritis

  • Look for inflammatory features: morning stiffness >30 minutes and improvement with activity.
  • Differentiate RA from osteoarthritis and crystal disease like gout before diagnosing RA.
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