In this podcast, rheumatologist Vanessa L. Kronzer discusses rheumatoid arthritis (RA), including its clinical manifestations, challenges in diagnosis, and effective treatment and management options. Topics covered include risk factors, atypical presentations, use of x-rays for diagnosis, and management with drugs like methotrexate and TNF inhibitors. They also explore achieving remission and burnt out RA.
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Key Risk Factors And Demographics
Rheumatoid arthritis (RA) is more common in women and peaks in the 30s and again in the 50s–60s.
Smoking and obesity substantially increase RA risk, with smoking raising risk ~3-fold.
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Classic Versus Atypical Presentations
Classic RA affects symmetrical small joints like MCPs, PIPs, wrists and MTPs but many cases are atypical.
RA can present palindromically with episodic attacks that come and go like gout.
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How To Differentiate RA From Other Arthritis
Look for inflammatory features: morning stiffness >30 minutes and improvement with activity.
Differentiate RA from osteoarthritis and crystal disease like gout before diagnosing RA.
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Rheumatologic problems are some of the most common health conditions we see as primary care professionals. In many cases, taking months and sometimes years to properly diagnose, rheumatologic conditions can become frustrating for both the provider and the patient. There are a variety of new tests available to help us establish a diagnosis, as well as multiple new and effective treatment options. This episode is part of a seven-episode mini-series on Mayo Clinic Talks dedicated to rheumatologic health problems to aid in the recognition, diagnosis, and treatment for your patients. Please find these episodes where you listen to podcasts or on ce.mayo.edu.
Rheumatoid arthritis is a chronic inflammatory, autoimmune disorder. While it typically results in a symmetric and erosive arthritis, many patients have an atypical presentation and up to 40% of those with rheumatoid arthritis have extra-articular manifestations. It tends to be progressive over years and can be quite debilitating. Fortunately, there are some new treatments available which have given our patients hope of a remission from this disease. This podcast will explore rheumatoid arthritis and we’ll discuss its clinical manifestations, how to establish a diagnosis and its management. Our guest is Vanessa L. Kronzer, M.D., from the Division of Rheumatology at the Mayo Clinic.