LONGEVITY with Nathalie Niddam

#379: The NEW Biohacking Stack For Gut Healing and Lifelong Vitality | Kiran Krishnan & Forrest Smith

15 snips
Oct 17, 2025
In this conversation, microbiologist Kiran Krishnan focuses on the vital role of gut health and spore-based probiotics while Forrest Smith discusses his pioneering work with red and near-infrared light therapy. They explore the surprising connections between gut and brain health, including the impact of leaky gut on neurodegeneration. Forrest shares insights from his own experiments with red light on the abdomen. Together, they delve into actionable strategies for enhancing longevity and systemic health through the synergy of probiotics and photobiomodulation.
Ask episode
AI Snips
Chapters
Transcript
Episode notes
INSIGHT

Abscopal Gut-to-Brain Effects

  • Remote (abscopal) red/near-infrared treatment of the gut can produce measurable brain benefits even without local brain treatment.
  • Forrest Smith highlighted animal and lab studies showing gut phototherapy affects dopamine and brain outcomes over weeks.
INSIGHT

Parkinson’s Often Starts In The Gut

  • Parkinson's pathology often begins in the enteric nervous system with early constipation and alpha-synuclein accumulation.
  • Kiran Krishnan links gut inflammation and LPS translocation to neurodegeneration and mood disorders.
INSIGHT

Endotoxin Link Between Gut And Alzheimer’s

  • Gut-derived endotoxins (LPS) have been found in Alzheimer's brain tissue and drive neuroinflammation and microvascular damage.
  • Photobiomodulation may repair tight junctions in gut and brain, attacking both source and target of inflammation.
Get the Snipd Podcast app to discover more snips from this episode
Get the app