Oncotarget
ER Expression Multiclonality in DCIS: Clinical & Future Insights
Aug 29, 2023
Dr. Mangesh A. Thorat discusses the multiclonality of ER expression in DCIS and its implications on personalized treatment outcomes. The podcast dives into the significance of clonal methodology in understanding ER expression in breast cancer.
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Quick takeaways
- Investigating multiclonality of ER expression in DCIS for personalized treatment insights.
- Emphasizing the need for further research on clonal populations in DCIS for improved clinical outcomes.
Deep dives
ER Expression in DCIS
Exploring the multiclonality of ER expression in DCIS, the research paper emphasizes the significance of investigating prognostic and predictive biomarkers in Dachal carcinoma in situ. By highlighting the inadequacy of existing data in personalizing DCIS treatment, the study introduces a new clonal method for evaluating ER expression to enhance clinical outcomes. The findings suggest that current misclassifications of multiclonal cases as ER positive impact prognosis, indicating the necessity to reclassify them as ER negative for more accurate clinical management.
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