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Mangesh A. Thorat

Expert in breast cancer research and clinical implications of estrogen receptor status in ductal carcinoma in situ (DCIS)

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Aug 29, 2023 • 5min

ER Expression Multiclonality in DCIS: Clinical & Future Insights

Dr. Mangesh A. Thorat discusses the multiclonality of ER expression in DCIS and its implications on personalized treatment outcomes. The podcast dives into the significance of clonal methodology in understanding ER expression in breast cancer.
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Aug 1, 2023 • 3min

Multiclonality of Estrogen Receptor Expression in Ductal Carcinoma in Situ (DCIS)

Exploring the significance of ER expression in DCIS, a pivotal study showed lack of ER linked to 3-fold risk of recurrence. ER expression in DCIS is multi-clonal with important clinical implications. Some ER-positive DCIS cases also contained ducts lacking ER expression.