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Wild Health Podcast

What Dr. Peter Attia Gets Wrong About DNAm Aging Clocks

Dec 6, 2023
The hosts debunk Dr. Peter Attia's points about the predictive value of aging clocks and offer an updated view. They discuss the evolution of epigenetic clocks and the use of multi-omic markers for disease prediction. The significance of longitudinal data in biologic age testing is explored, along with the benefits of the Dine and Pace method for assessing stress response. Advancements in understanding DNA methylation aging clocks and the importance of using blood tests for accuracy are also discussed.
46:03

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Quick takeaways

  • The new generation of biological clocks, such as Dunedin Pace and Omic Age, provide improved precision and reduced variability compared to previous clocks, allowing for accurate estimation of biological age and prediction of disease risk and mortality.
  • The practical application of these clocks allows for personalized health decisions, interventions, and lifestyle changes, providing insights into specific organ systems and measuring the effectiveness of interventions in slowing down aging and improving health outcomes.

Deep dives

New generation clocks estimate biological age accurately

The podcast episode discusses the new generation of clocks that accurately estimate biological age. These clocks, such as Dunedin Pace and Omic Age, have improved precision and reduced variability compared to previous clocks. They take into account longitudinal data, tracking changes in biomarkers over time, and can predict the risk of diseases and mortality with high accuracy. The clocks also provide insights into specific organ systems and potential interventions. The podcast emphasizes the practical application of these clocks for individual health decisions and shows how they can guide interventions and measure the effectiveness of lifestyle changes.

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