In this episode, Tom Guilliams and Dr. Jaclyn Smeaton delve into the complexities of the HPA axis, exploring its role in stress response, metabolic regulation, and overall health. They discuss the multifaceted nature of cortisol, its impact on glucose levels, and how early life stressors can shape HPA axis function.  

This episode also explores: 

• The significance of perceived stress 
• How circadian rhythm influences HPA axis function 
• The intricate connections between obesity, inflammation, and the HPA axis  
• Holistic approaches to managing HPA axis dysfunction, including the use of adaptogens and the importance of physical activity 
• Gender differences in stress response and the factors that contribute to burnout 

Show Notes:
Learn more about Tom Guilliams and his research organization, Point Institute. 

Check out other episodes of the DUTCH Podcast with Tom Guilliams: What’s the Deal with the Pregnenolone Steal? and HPA Axis: A Whole-Body Stress Response System. 

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