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From Our Neurons to Yours
How the brain helps cancers grow | Michelle Monje
Aug 15, 2024
In a compelling discussion, Stanford neuro-oncologist Michelle Monje sheds light on her groundbreaking work in cancer neuroscience. She reveals how deadly brain tumors engage with healthy brain tissue, relying on electrical signals to thrive. Monje explores the surprising dependency of many cancers on the nervous system, opening up new avenues for treatment. The conversation dives into the challenges of treating high-grade gliomas in children and the dynamic interplay between gliomas and neurons, highlighting innovative therapeutic strategies on the horizon.
21:27
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Quick takeaways
- Michelle Monje's groundbreaking research reveals that deadly brain tumors actively depend on the surrounding brain's electrical activity for their growth.
- The discovery of tumor-neuron synapse interactions opens new strategies in oncology, allowing for potential treatment optimization through neuromodulation.
Deep dives
The Emergence of Cancer Neuroscience
A groundbreaking discovery in cancer neuroscience highlights the critical link between deadly brain tumors and the healthy brain tissue surrounding them. Research indicates that these tumors, particularly diffuse midline gliomas, not only connect physically to healthy tissue but also rely on its electrical activity for growth and spread. This finding suggests that the nervous system's innervation is integral to cancer survival across various types, indicating a revolutionary new approach for oncology. The concept emerged from observations that most cancers could potentially hijack similar mechanisms that are fundamental to the nervous system.
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Discover
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