In a compelling discussion, Stanford neuro-oncologist Michelle Monje sheds light on her groundbreaking work in cancer neuroscience. She reveals how deadly brain tumors engage with healthy brain tissue, relying on electrical signals to thrive. Monje explores the surprising dependency of many cancers on the nervous system, opening up new avenues for treatment. The conversation dives into the challenges of treating high-grade gliomas in children and the dynamic interplay between gliomas and neurons, highlighting innovative therapeutic strategies on the horizon.