Quick takeaways

• There are various devices and techniques, such as bronchodilators, positive expiratory pressure flutter devices, and cough assist machines, that can enhance airflow and aid in mucus movement for effective airway clearance.

• Mucolytics like hypertonic saline and dornase alpha have demonstrated effectiveness in certain conditions like cystic fibrosis and non-cystic fibrosis bronchiectasis, but their use in other conditions lacks strong evidence and should be based on the specific diagnosis and clinical presentation of the patient.

• Chronic pulmonary aspiration, which can be caused by factors like reflux, aspiration of oral secretions, or impaired cough clearance, should be investigated and managed to reduce airway inflammation, improve clearance, and prevent complications through timely intervention and collaboration with healthcare professionals.

Deep dives