Dr. Ruscio Radio, DC: Health, Nutrition and Functional Healthcare

New IBS Test with IBS & SIBO Researcher Dr. Mark Pimentel

Apr 24, 2019
Dr. Mark Pimentel, a gastroenterologist known for IBS and SIBO research, explains a blood test that links food-poisoning toxin antibodies to disrupted gut motility. He discusses how the IBS-smart test works, its potential to save time and money, how clinicians order it, antibody thresholds for severity, and ongoing trials aiming to remove pathogenic antibodies and better characterize small bowel microbes.
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INSIGHT

Food Poisoning Can Trigger Gut Autoimmunity

  • Food poisoning with CdtB can trigger antibodies that cross-react with human vinculin and impair gut motility.
  • This autoimmune cascade links post-infectious IBS, SIBO, and chronic motility dysfunction.
ADVICE

Use IBS‑Smart As First‑Line Screening

  • Use the IBS-smart blood test as a first-line screen to rapidly identify IBS and avoid unnecessary invasive testing.
  • A dual-positive test yields ~98% probability of IBS versus IBD, saving time and cost for patients and healthcare.
ADVICE

How To Order The Test

  • Ask your clinician to order the IBS‑smart kit; the physician draws blood and mails it to the lab for insurance billing.
  • The test currently requires clinician order and costs $220 before insurance adjustments.
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