The Resetter Podcast with Dr. Mindy

Heart Disease, Hormones & LPa Explained by Dr. Darshan Shah

Jan 27, 2025
In this enlightening discussion, Dr. Darshan Shah, a health specialist and founder of Next Health, unpacks the dangers of high Lp(a) levels in heart disease, especially for women. He emphasizes that lifestyle changes alone may not suffice in managing this risk factor. The conversation introduces innovative treatments like Total Plasma Exchange and highlights the importance of modern blood testing methods. Shah advocates for proactive health strategies, educating listeners on the interplay of genetics, lifestyle, and personalized medicine for optimal well-being.
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INSIGHT

Lp(a) and Menopause

  • Cardiovascular disease is a significant concern for menopausal women, especially with estrogen loss.
  • Lp(a), a genetic marker, adds another dimension to cardiovascular risk assessment, independent of hormones.
ANECDOTE

Personal Lp(a) Concerns

  • Dr. Pelz's friend, TJ, died suddenly of a heart attack at 54, potentially due to high Lp(a).
  • Her grandfather also died of a stroke at a similar age, raising further concern about a genetic link.
INSIGHT

Lp(a) Cholesterol Risk

  • Lp(a) is a sticky cholesterol protein, resistant to lifestyle changes, that contributes to plaque buildup.
  • High Lp(a) increases cardiovascular risks, even without other risk factors like high blood pressure.
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