Wild Health Podcast cover image

Wild Health Podcast

MTOR Unveiled Part 2: Protein, MTOR, and Muscle Growth

Aug 23, 2023
Discover the science behind muscle growth, protein synthesis, and MTOR activation. Learn how to maximize fasting without muscle loss, the impact of protein intake on MTOR and longevity, and the intricate relationships between variables in medicine. Unveil the complexity of protein and muscle growth, and explore the benefits and considerations of a plant-based protein diet.
33:57

Podcast summary created with Snipd AI

Quick takeaways

  • Activation of mTOR is crucial for muscle growth and can be achieved through factors such as protein intake, leucine, insulin, and glucose.
  • The impact of protein on longevity varies depending on age, with higher protein intake being beneficial for individuals over 65, but potentially detrimental for those below 65, especially from animal sources.

Deep dives

Protein intake and muscle development

Protein intake plays a crucial role in muscle development and synthesis. Activation of the anabolic signaling pathway, mTOR, is essential for muscle growth. Factors such as eating amino acids, particularly leucine, insulin-like growth factor, cellular stress, insulin, and glucose can activate mTOR. Conversely, glucagon and cortisol can inhibit mTOR. Activation of mTOR leads to increased protein synthesis, hypertrophy of muscle cells, activation of satellite cells for muscle repair and growth, and inhibition of muscle protein breakdown. Understanding the connection between protein intake and muscle development is important for optimizing exercise and resistance training.

Get the Snipd
podcast app

Unlock the knowledge in podcasts with the podcast player of the future.
App store bannerPlay store banner

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode

Save any
moment

Hear something you like? Tap your headphones to save it with AI-generated key takeaways

Share
& Export

Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode