GABA’s Role in Reducing Stress, Anxiousness, and Improving Sleep Quality with Dr Scott Sherr
Nov 10, 2023
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Dr Scott Sherr, COO of @Troscriptions, talks about GABA's role in reducing stress and improving sleep quality. He discusses why regular GABA supplements don't work, the effect of alcohol and benzos on GABA, and potential causes for restless leg syndrome. They also touch on the health benefits of supplementing honokiol, cordycepin, and adenosine.
GABA and glutamate are the main neurotransmitters responsible for 80% of brain's neurotransmission, not dopamine and norepinephrine as commonly believed.
Trozi, a sleep formula, contains agarin from the fly agaric mushroom which acts as a GABA agonist, enhancing the GABA system to regulate sleep.
Melatonin, found in Trozi, plays a crucial role in maintaining circadian rhythms and combating inflammation and infection.
Deep dives
Trocom: A synergistic combination of substances to promote relaxation and calmness
Trocom is a product developed by Troscriptions, known for their methylene blue trochies, that contains a combination of substances including cannabinoids, kava, and vitamin B3-bound GABA. The vitamin B3 allows GABA to reach the brain and bind to its receptors, promoting inhibitory neurotransmission and calming effects. Trocom is designed to take off the edge of stress and anxiety, enhance relaxation, and improve focus without causing drowsiness.
Trozi: A sleep formula with agarin from the fly agaric mushroom
Trozi is another product by Troscriptions that focuses on improving sleep. It contains agarin, an ingredient derived from the fly agaric mushroom, which has interesting effects on the GABA receptors. Agarin helps modulate the sleep systems in the brain, making it easier to fall asleep, stay asleep, and go back to sleep if awakened during the night. Trozi is formulated to target the areas of the brain that are crucial for sleep, offering a natural alternative to sleep medication.
The significance of GABA in brain function and overall well-being
GABA, the most important neurotransmitter for calming the brain, plays a vital role in various aspects of mental and physical health. Around 80% of the brain's neurotransmission involves glutamate and GABA, rather than serotonin or dopamine as commonly believed. GABA deficiency can lead to symptoms such as anxiety, depression, poor sleep, short temper, and even systemic symptoms like IBS and chronic pain. Understanding the conversion of glutamate into GABA, the nutrients required for this process (vitamin B6 and magnesium), and the significance of the GABA receptor system can provide insights into optimizing brain function and overall wellness.
The Power of Agaric Compound in Sleep Regulation
One of the compounds found in the fly agaric mushroom, known as agarin, is being used in a sleep formula called Trozi. Agarin acts as a GABA agonist and enhances the GABA system, which helps regulate sleep and prevent waking up during nightmares. The fly agaric mushroom contains two main compounds, ibotenic acid and agarin. Ibotenic acid causes hallucinations and psychedelic experiences but is neurotoxic, while agarin binds to the GABA site and has a longer half-life, providing a consistent amount of GABA in the system. Trozi contains a low dose of agarin, ensuring purity and effectiveness.
The Efficacy and Controversies of Melatonin
Trozi, a sleep formula, includes melatonin, which helps regulate circadian rhythms and maintain sleep. Melatonin production naturally decreases with age, making supplementation critical for older individuals. Controversy surrounds melatonin's impact on testosterone production, but at physiologic doses, there is no evidence of negative effects. Melatonin's antioxidant properties make it valuable for combating inflammation and infection. Higher doses of melatonin may be used in emergency situations or for acute stress, but caution is needed in their use. Overall, a comprehensive sleep formula like Trozi is essential for better sleep quality and overall health.
Gamma-aminobutyric acid, also known as GABA, is the chief inhibitory neurotransmitter in the mammalian nervous system. According to Dr Scott Sherr, dopamine and norepinephrine get too much credit when the real stars of the show that make up 80% of our brain's neurotransmission are GABA and glutamate.
COO of @Troscriptions Dr Scott talks about the ingredients found in TroCalm and their new sleep formula TroZZZ and how they both support GABA production. He says why regular GABA supplements don't work, common symptoms of GABA deficiency, the effect of alcohol and benzos on GABA, why they added an extract from the Amanita Muscaria mushroom into their sleep formula, why he believes gamma hydroxybutyrate (GHB) is wrongly demonized, potential causes for restless leg syndrome, and the health benefits of supplementing honokiol, cordycepin and adenosine.
