
Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition The Three S Model: Stimulus, Supply and Support for Cognitive Health and Dementia Risk | Dr Tommy Wood
Jan 12, 2026
In this engaging discussion, Dr. Tommy Wood, a physician and brain health researcher, delves into his innovative Three S model—stimulus, supply, and support—crucial for cognitive function. He emphasizes cognitive challenges as the primary stimulus for brain adaptation. The conversation explores the significance of key nutrients like omega-3s, B vitamins, and vitamin D in reducing dementia risk while highlighting the vital roles of blood flow and sleep for overall support. Discover how chronic stress and nutrient deficiencies can impact brain health!
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Three S Model Drives Brain Adaptation
- Cognitive health relies on a Three S model: Stimulus, Supply, and Support driving brain adaptation.
- Stimulus (cognitive challenge) is primary, while supply and support enable and optimize adaptation.
Make Cognitive Challenge Primary
- Prioritize cognitive challenge as the core stimulus for building and preserving brain networks.
- Use nutrition and sleep to enhance gains, but don't rely on them without mental challenge.
Blood Flow And Vascular Health Matter
- Supply includes blood flow, oxygen, and fuels like glucose, ketones, or lactate to active brain regions.
- Cardiovascular and vascular health are thus central to brain function and dementia risk.

