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The Fellow on Call: The Heme/Onc Podcast
Episode 095: Introduction to CLL/SLL
Mar 6, 2024
Dive into the world of chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) as the hosts share personal clinical experiences. Discover insights about diagnosing CLL, the mystery of smudge cells, and the importance of B cells. They debunk common myths and emphasize that patients can often live well without aggressive treatment. Plus, explore advancements in risk stratification and the role of molecular testing in tailored patient care. And don’t miss out on some recommended winter wines to enjoy while you listen!
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Quick takeaways
- Understanding the distinction between CLL and SLL is crucial for accurate diagnosis and managing patient expectations regarding prognosis.
- Flow cytometry plays a vital role in diagnosing CLL by evaluating lymphocyte characteristics and differentiating between benign and malignant conditions.
Deep dives
Introduction to Chronic Lymphocytic Leukemia (CLL)
Chronic lymphocytic leukemia (CLL) is characterized by having high white blood cell counts, but many patients can be asymptomatic despite the presence of leukemic cells. Often, patients present with isolated leukocytosis detected during routine lab testing. It is essential to reassure patients and educate them about the normal variations in disease progression, as some individuals may remain relatively healthy for an extended period. Understanding these dynamics helps clinicians determine when to initiate treatment and how to manage patient expectations.
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Discover
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Listen to the best highlights from the podcasts you love and dive into the full episode