The Fellow on Call: The Heme/Onc Podcast

Rouleaux University Medical Center
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Oct 14, 2026 • 0sec

Episode 167: Pancreatic Cancer Series, Pt. 2 – Resectable Disease

Pancreatic cancer management takes center stage, from defining resectable disease and achieving an R0 margin to the Whipple procedure and the case for high-volume surgical teams. The discussion traces modern adjuvant options, compares surgery-first with neoadjuvant strategies, explores biliary stenting decisions, and previews emerging KRAS-targeted treatments.
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Oct 7, 2026 • 0sec

Episode 166: Pancreatic Cancer Series, Pt. 1 – Biology, Diagnosis, and Staging

A new case of painless jaundice, weight loss, and diabetes opens a deep dive into pancreatic cancer. Explore risk factors and hereditary syndromes, how tumor location shapes symptoms, and the roles of CT, MRI, EUS, and ERCP. The discussion also covers CA 19-9 pitfalls, precursor lesions, key mutations, molecular testing, and vascular criteria that determine resectability.
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Sep 23, 2026 • 0sec

Episode 165: CLL Updates Series, Pt. 2 – Relapsed/Refractory in 2026

A relapsed CLL case sets the stage for when recurrence warrants treatment and how BTK mutation testing guides therapy. The discussion explores sequencing BTK inhibitors and venetoclax, retreatment strategies, pirtobrutinib triplet data, real-world CAR T outcomes, bispecific antibodies, and promising BTK degraders.
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6 snips
Sep 16, 2026 • 0sec

Episode 164: CLL Updates Series, Pt. 1 – Frontline Therapy in 2026

A newly diagnosed CLL case sets the stage for a tour of modern frontline care. The discussion covers treatment triggers, Richter transformation, FISH and IGHV risk assessment, and the shift from chemoimmunotherapy to BTK inhibitors and venetoclax-based combinations. AMPLIFY, SEQUOIA, and CLL17 take center stage, alongside toxicity tradeoffs, TP53 uncertainty, and the evolving role of MRD.
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Sep 9, 2026 • 0sec

Episode 163: Head and Neck Cancer Series, Pt. 5 – Recurrent, Relapsed, and Metastatic Disease

Recurrent head and neck cancer takes center stage through a challenging laryngeal cancer case. The discussion explores distinguishing recurrence from a second primary, biopsy and biomarker workup, salvage surgery and re-irradiation, CPS-guided immunotherapy, treatment after progression, nasopharyngeal cancer’s distinct pathway, oligometastatic disease, and early supportive care.
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Sep 2, 2026 • 0sec

Episode 162: Head and Neck Cancer Series, Pt. 4 – Discussion with Radiation Oncology

David Palma, a radiation oncologist and clinician-scientist at Western University, brings radiation oncology into focus for head and neck cancer. They explore treatment planning, IMRT, fractionation, HPV-positive disease, post-treatment PET scans, larynx preservation, re-irradiation, oligometastatic disease, and the ongoing proton-versus-photon debate.
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Aug 19, 2026 • 0sec

Episode 161: Career Development Series- Building a Career in Clinical Research

Hanny Al-Samkari, clinical hematologist and investigator at Massachusetts General Hospital and associate professor at Harvard Medical School. He breaks down types of clinical research and how trainees can jump in. Learn practical starts from retrospective studies to trials. Hear about daily life of a clinical investigator, training in statistics, and balancing clinical work with research.
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Aug 12, 2026 • 0sec

Episode 160: Head and Neck Cancer Series, Pt. 3 – Discussion with ENT

Michael Topf, an otolaryngology professor and head and neck cancer surgeon at Vanderbilt, discusses how surgeons assess candidacy and plan treatment. Topics include oral cavity reconstruction, margin assessment, elective neck dissection, perioperative pembrolizumab, TORS for HPV-positive disease, organ preservation, salvage surgery, and the multidisciplinary team supporting patients.
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Aug 5, 2026 • 0sec

Episode 159: Head and Neck Cancer Series, Pt. 2 – Locoregional Disease

A focused tour of locoregional head and neck cancers with case-based takes on oral cavity, oropharynx, and larynx management. Conversations cover surgery-first strategies, when to add chemoradiation, and why high‑dose cisplatin became standard. Alternatives like weekly cisplatin or carboplatin‑paclitaxel, the niche for induction chemo, and perioperative immunotherapy trials are highlighted.
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Jul 29, 2026 • 0sec

Episode 158: Head and Neck Cancer Series, Pt. 1 - Introduction

A kickoff to a head and neck cancer series using a painless neck mass case. They distinguish HPV-driven and carcinogen-driven cancers and explain p16 and HPV biology. Practical topics include how to work up a neck mass, imaging and biopsy strategies, and locating an unknown primary. Listeners also get a clear tour of cervical lymph node levels and staging nuances for HPV-positive disease.

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