Guest:
Dr. Florian Krammer is a Professor of Vaccinology at Icahn School of Medicine at Mount Sinai. His lab focuses on understanding broadly-reactive immune responses against the surface glycoproteins of RNA viruses such as influenza, with the goal to develop better vaccines and novel therapeutics. He talks about his lab’s shift to COVID-19 research, strategies for vaccine development, and how we can prepare for future pandemics.
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The Immunology Science Round Up
The Microbiome’s Effects on CAR T Therapy Outcomes – Exposure to broad spectrum antibiotics prior to CAR T therapy was associated with worse survival and increased neurotoxicity.
Identifying Genes That Improve T Cell Proliferation – Researchers tested over 12,000 genes and identified positive regulators of T cell functions.
Fungi in Inflammatory Bowel Disease – Scientists identified fungal strains that induce intestinal inflammation in patients with ulcerative colitis.
Neuroimmune Communication via Cerebrospinal Fluid – Cerebrospinal fluid gains direct access to the skull bone marrow niches and regulates immune responses.
Image courtesy of Dr. Florian Krammer