The Energy Blueprint Podcast Dr. Gabrielle Lyon - LONGEVITY Do This To BUILD MUSCLE & LIVE Longer!
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Jul 5, 2025 
Dr. Gabrielle Lyon, founder of the Institute for Muscle-Centric Medicine®, discusses the overlooked driver of chronic illnesses, the truth about calories in-calories out, managing cholesterol without statins, a new way to view obesity, and avoiding mitochondrial decline in older age.
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Muscle: The Organ of Longevity
- Skeletal muscle is the largest endocrine organ and central to metabolism and longevity.
- It regulates glucose disposal, burns fatty acids, and releases anti-inflammatory myokines during exercise.
Under-Muscling Drives Metabolic Health
- Being under-muscled causes metabolic issues more than having excess fat.
- Healthy skeletal muscle is essential to store glucose and burn fatty acids, impacting overall health.
Preserve Muscle with Protein + Exercise
- Prioritize higher protein intake (about double the RDA) during calorie restriction to preserve muscle.
- Combine adequate protein with exercise, even walking and stretching, to maintain lean mass.