The Proof with Simon Hill

The 5 most important protein questions answered with the latest science | Dr Matthew Nagra

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Nov 10, 2025
Dr. Matthew Nagra, a clinical nutrition researcher specializing in protein, muscle, and public health, joins to tackle common protein misconceptions. They discuss optimal protein intake for muscle growth, revealing 1.2–1.6 g/kg as effective. The chat highlights that resistance training is more crucial than protein alone for gains, and plant proteins are linked to lower chronic disease risk. Matthew dives into the environmental benefits of plant sources and dispels myths around high protein intake and its risks. Get ready for evidence-based insights on nutrition!
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ADVICE

Practical Protein Targets For Muscle

  • Aim for about 1.2–1.6 g/kg bodyweight of protein daily to support muscle and strength gains when paired with resistance training.
  • Increase toward 1.6 g/kg only if you want to squeeze out modest additional gains; >1.6 g/kg shows no clear extra benefit.
INSIGHT

Source Matters Less Than Total Intake

  • When protein intake is matched, clinical trials show no meaningful difference in muscle or strength gains between plant and animal protein.
  • Total protein amount and resistance training drive outcomes more than protein source.
ADVICE

Focus On Daily Protein And Training

  • Distribute protein sensibly but prioritize total daily intake; even uneven meal patterns didn't change daily muscle protein synthesis in controlled trials.
  • Pair protein with resistance training to get the benefit; protein alone has little effect.
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