The DUTCH Podcast
HPA axis: A Whole-Body Stress Response System with Tom Guilliams, PhD
Nov 14, 2023
Tom Guilliams, PhD, discusses the HPA axis's role in stress management and how early life stress can impact it permanently. He debunks myths about adrenal fatigue and highlights resources for learning more. The podcast explores cortisol regulation, DHEA's counteraction to cortisol, morning cortisol testing, and the evolution of HPA axis research.
44:12
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Quick takeaways
- The HPA axis regulates stress beyond adrenal glands, impacting brain functions and overall health.
- Salivary cortisol testing, including CAR analysis, provides insights into HPA axis function and avoids adrenal fatigue misconceptions.
Deep dives
Importance of Understanding the HPA Axis
The HPA axis plays a crucial role in managing stress and regulating various bodily functions beyond just the adrenal glands. Stress impacts the brain, interpreting information and sending signals to different parts of the body. However, popular misconceptions like adrenal fatigue oversimplify the complex interactions of the HPA axis, including the hypothalamus and pituitary. By recognizing the broader impact of the HPA axis, clinicians can better understand how stress affects glucose management, circadian rhythms, metabolism, and overall health.
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