#346: How Wearables, Biological Age Tests, And AI Are Shaping the Future Of Longevity With David Korsunsky

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Jun 24, 2025

David Korsunsky, founder of Heads Up Health and a pioneer in biohacking, shares insights on the evolution of health data tracking. He explores the impact of wearables in managing conditions like diabetes and autoimmune diseases. Korsunsky emphasizes the importance of sleep, hydration, and micro-experiments in optimizing wellness. The conversation dives into cutting-edge tools for biological age testing and the significance of core metrics like HRV and blood sugar. Tune in for practical approaches to harness personal health data for longevity!

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ANECDOTE

Early Biohacking Conference Story

Dave Korsunsky started Heads Up Health with little money and a folding table at Dave Asprey's early biohacking conference.
He tried to convince skeptical attendees about the future importance of health data and precision tracking.

INSIGHT

Data-Driven Health Revolution

In the last decade, health tech grew exponentially from obscurities to mainstream consumer tools.
Daily health measurement and micro experiments enable real-time, data-driven health optimization.

ADVICE

GLP-1 Use Requires Data & Technique

Establish a baseline using DEXA or in-body scans before starting GLP-1 or peptide protocols.
Ensure proper technique with protein intake and hydration to minimize muscle loss during weight loss.

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Today I’m joined by my friend and fellow biohacker, Dave Korsunsky, founder of Heads Up Health. In this episode, we take you on a journey through the evolution of biohacking—from the early days when continuous glucose monitors were a novelty and cryotherapy sounded like science fiction, all the way to the sophisticated, data-driven tools we have at our fingertips today.

What we discuss:

Dave’s journey: Heads Up Health and the rise of health data ... 00:08:18

Making sense of health metrics: Knowing if protocols work ... 00:10:06

GLP-1s: muscle loss risks, proper technique, and hydration ... 00:16:18

Clinical stories: HRV, autoimmune disease, and diabetes management ... 00:25:57

The foundational power of sleep, hydration, and micro-experiments ... 00:34:14

Core metrics: HRV, blood sugar, sleep, and their significance ... 00:40:46

The promise and impact of new longevity diagnostics ... 00:50:42

No-equipment longevity tests: grip, hang, balance, sit-to-stand ... 01:00:31

Aggregate your data and run micro-experiments ... 01:05:25

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