Core IM | Internal Medicine Podcast

#96 The Hgb bump: Mind the Gap Segment

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Jan 5, 2022
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INSIGHT

One-to-One Bump

  • The "one gram per deciliter" hemoglobin bump isn't always true.
  • This rule of thumb is suspiciously convenient and warrants investigation.
INSIGHT

Blood Donation Math

  • Standard US blood donation is 525 ml (500 ml donation + 25 ml for testing).
  • A donor with 13 g/dL hemoglobin donates approximately 65 grams of hemoglobin.
INSIGHT

Functional Hemoglobin

  • Due to processing and storage, only 85% of donated red blood cells remain viable.
  • A 65g hemoglobin donation results in 55g of functional hemoglobin for the patient.
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