Oncotarget

Osteopontin Induces Mitochondrial Biogenesis in Deadherent Cancer Cells

Dec 14, 2023
Dr. Georg F. Weber, a researcher from the University of Cincinnati, talks about his research paper on 'Osteopontin induces mitochondrial biogenesis in deadherent cancer cells'. He discusses the unique metabolism of metastasizing cells and their preference for glycolysis. The chapter also explores the connection between mitochondrial activation and biogenesis in cancer cells, with a focus on the role of osteopontin. Additionally, peroxide production in cancer cells and its impact on cancer metastasis is discussed, revealing surprising findings about the involvement of mitochondrial decoupling and SLC7A11 channel.
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