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Osteopontin Induces Mitochondrial Biogenesis in Deadherent Cancer Cells

Oncotarget

CHAPTER

Peroxide Generation and its Impact on Cancer Metastasis

This chapter delves into the surprising findings on peroxide production in cancer cells, revealing that mitochondrial decoupling is not involved but rather acts upstream of PGC1. The discussion also highlights the association of the SLC7A11 channel with redox activity and the implications of suppressing biogenesis-inducing mechanisms in reducing tumor mass dissemination.

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