The Curious Clinicians

64 - Stopping the Shakes

Feb 8, 2023
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ANECDOTE

Meperidine's Power

  • Hannah Abrams sometimes uses meperidine to treat rigors in specific situations.
  • This involves stabilizing shaking, hypertensive, and desaturating patients.
INSIGHT

Meperidine's History

  • Meperidine, the first synthetic opioid, gained popularity as a morphine alternative during wartime.
  • Initially thought less addictive, this proved false, leading to its decline.
INSIGHT

Meperidine's Effectiveness

  • A meta-analysis of 94 studies showed meperidine's effectiveness in treating shivering.
  • Its risk ratio of 2.2 surpasses fentanyl's 1.2.
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