The Intern At Work: Internal Medicine

26. Heart of the Infection - Infective Endocarditis

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Apr 28, 2019
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INSIGHT

How Endocarditis Develops

  • Infective endocarditis is inflammation of the endocardium usually from bacteremia that seeds heart valves.
  • Bacteria form adhesive biofilms on valves, creating vegetations that resist dislodgement and cause emboli or valve dysfunction.
INSIGHT

Microbes That Should Trigger Echo

  • Common organisms include Staphylococcus aureus, Streptococcus viridans, Streptococcus bovis, and Enterococcus.
  • A blood culture positive for these organisms should prompt echocardiography to evaluate for endocarditis.
ADVICE

History And Exam Targets

  • Ask about indwelling lines, recent dental work, skin infections, and injection drug use when assessing suspected endocarditis.
  • Examine for track marks, abscesses, new murmurs, and signs of embolic or systemic complications.
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