The ADHD Adults Podcast Episode 199 ADHD & Neuroplasticity
Nov 17, 2025
Dive into the fascinating world of neuroplasticity and its connection to ADHD. Discover how the brain rewires itself through learning and experiences. Explore the role of NMDA receptors in memory formation and their potential dysfunction in ADHD. Learn about how dopamine interacts with neuroplasticity, and the possibilities of enhancing it through cognitive interventions and mindfulness. Reflect on personal experiences with ADHD, treatment frustrations, and the hope that neuroplasticity brings for better support and outcomes.
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Listener Diagnosis Letter
- Danny from Transylvania wrote after receiving a recent ADHD diagnosis and described intrusive rumination and infinite loops.
- He said he got meds and therapy and thanked the hosts for their work.
Brain Lifelong Rewiring
- Neuroplasticity means the adult brain can rewire itself through experience and learning.
- Small cellular changes accumulate into large-scale network reorganizations that support recovery and skill learning.
NMDA: The Plasticity Switch
- NMDA receptors act as a molecular switch for whether connections strengthen or weaken.
- They require specific conditions to open and trigger long-term potentiation or depression.
