
Chasing Life What You Need to Know About Hormone Therapy
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Nov 18, 2025 Dr. Mary Claire Haver, an OB-GYN and certified menopause practitioner, joins to discuss the FDA's potential removal of the black box warning on hormone treatments for menopause. They explore the implications of this decision and emphasize the importance of clinical evaluations for symptoms rather than relying solely on blood tests. Additionally, they provide insights on when to start hormone therapy, its duration, alternatives for those who can’t take HRT, and the roles of non-hormonal medications in alleviating menopause symptoms.
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Black Box Removal Changes Risk Picture
- The FDA plans to remove the black box warning on many menopausal hormone therapies, which may increase treatment access and prescriptions.
- Reanalysis shows risks vary by age at start, timing since menopause, and formulation, altering prior risk conclusions.
Timing Alters Hormone Therapy Risks
- The 2003 Women's Health Initiative included women with average age 63, many years past menopause, which influenced risk findings.
- Starting hormone therapy within 10 years of menopause or before 60 may reduce cardiovascular, Alzheimer's, and fracture risks.
Personal Conversations Reflect Widespread Concern
- Sanjay Gupta notes personal conversations about HRT with his mother and wife, reflecting how widespread the issue is.
- He suggests nearly every woman in America facing perimenopause or menopause has considered HRT.



