

The Truth About Aging Clocks And Death
Jan 3, 2025
Brian Johnson, a prominent biohacker and enthusiast of longevity, shares fascinating insights on aging in this discussion. He unpacks DNA methylation clocks and their role in biological age assessment. The conversation dives into the significance of health interventions and personal experiences with therapies, challenging traditional markers of aging. Johnson also introduces gamification in health tracking, making research participation more engaging. Ultimately, he emphasizes the nuances between biological and chronological age and the need for cautious interpretation of aging metrics.
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Six Clocks Experiment
- Brian Johnson experimented with six epigenetic age clocks and published the results.
- Headlines misrepresented his findings, claiming he reversed his age by 4.5 years.
Phenotypic Markers vs. Epigenetic Clocks
- While epigenetic clocks are interesting, phenotypic markers are superior indicators of health.
- However, blood tests needed for phenotypic markers are less accessible than epigenetic tests.
Epigenetic Clocks: Motivation vs. Misguidance
- Epigenetic clocks offer affordable, self-motivating health tracking.
- However, they may misguide interventions and lack validation for lifespan prediction.