James Fadiman, Ph.D., a leading psychedelic researcher known as the “father of microdosing,” teams up with Jordan Gruber, JD, MA, a transformational modality expert. They dive into microdosing psychedelics, discussing its benefits for creativity and mental health. Topics include various dosing protocols, the legal landscape, and the therapeutic potential for conditions like long COVID. They also explore the contrast between microdosing and traditional antidepressants, emphasizing personalized approaches and the evolving understanding of mental health treatment.
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insights INSIGHT
Microdosing Defined And Broad Benefits
Microdosing means taking sub-threshold amounts of psychedelics to remain functional and avoid full psychedelic effects.
James Fadiman and Jordan Gruber report broad benefits across mental, physical, and performance domains.
volunteer_activism ADVICE
Use 'Sub‑Threshold' Not 'Subperceptual'
Use the term "sub-threshold" rather than "subperceptual" to describe microdoses that avoid psychedelic visuals and breakthroughs.
Stay below the threshold so you can have an ordinary day while receiving benefits.
insights INSIGHT
Microdosing Is Already Widespread
Microdosing is a global phenomenon with reports from dozens of countries and millions of users in the U.S.
RAND estimated half of recent psilocybin users in 2023 were microdosing, indicating mainstream uptake.
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Jim talks with James Fadiman and Jordan Gruber about the findings in their recent book Microdosing for Health, Healing, and Enhanced Performance. They discuss the definition of microdosing, "subthreshold" vs "subperceptual," typical doses, current usage statistics & demographics, its legal status & classification history, LSD, psilocybin, why cannabis isn't suitable for microdosing, mechanisms of action, dosing protocols, anti-inflammatory effects, health applications, enhancement applications, contraindications & side effects, research methodologies & limitations, commercial potential, global adoption patterns, and much more.
Episode Transcript
Microdosing for Health, Healing, and Enhanced Performance, by James Fadiman and Jordan Gruber
The Psychedelic Explorer's Guide, by James Fadiman
Our Symphony of Selves, by James Fadiman and Jordan Gruber
JRS EP126 - Jordan Gruber & James Fadiman on Our Symphony of Selves
Autism on Acid, by Aaron Paul Orsini
Institute of Noetic Sciences
James Fadiman, Ph.D., is a prominent figure in the field of psychedelic research, particularly known for his work on microdosing psychedelics like LSD and psilocybin. Often called the “father of microdosing,” Fadiman has a long history in the study of psychedelics dating back to the 1960s, when he worked on studies involving LSD and creativity while at Stanford University. After psychedelics were banned in the U.S., Fadiman shifted his focus but returned to psychedelic research decades later. His book, The Psychedelic Explorer’s Guide: Safe, Therapeutic, and Sacred Journeys, has become a key resource for safe psychedelic exploration. In recent years, he has pioneered research on microdosing, examining its potential benefits for mental health, cognitive enhancement, and overall well-being.
Jordan Gruber, JD, MA, founded the early online Enlightenment.Com community. After practicing law at Cooley Godward and focusing on IP law at NASA’s Moffett Field, as well as working at GNOSIS Magazine, Jordan became “the Practical Wordsmith,” a writer, ghostwriter, editor, and writing coach speciliazing in transformational modalities and practices. Jordan has helped create cutting-edge works on everything from forensic audio and financial services to health, wellness, psychology, and spirituality. Recent editing credits include Cindy Lou Golin’s The Shadow Playbook (2023), Scott Rogers’s The Mindful Law Student (2022), and Lawrence Ford’s The Secrets of the Seasons (2020).
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