

The New Science Behind Tackling Depression
Sep 28, 2023
Join Philip Gold, a leading researcher of depressive illness and author of 'Breaking Through Depression', alongside Güneş Taylor, a science communicator at The Francis Crick Institute. They dissect the complexities of depression, comparing melancholic and atypical forms, and delve into the effects of early trauma. Their discussion introduces innovative treatment approaches, including SSRIs and psychedelics, advocating for a personalized and holistic perspective on mental health that challenges traditional views.
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Two Types of Depression
- Depression arises from environmental factors, stressors, trauma, combined with genetic predispositions.
- It manifests as two distinct types: melancholic and atypical depression.
Melancholic Depression
- Melancholic depression involves an overactive stress response, marked by anxiety, worthlessness, and loss of pleasure (anhedonia).
- Symptoms worsen in the morning and improve slightly in the evening.
Atypical Depression
- Atypical depression involves an underactive stress response, leading to disconnection, oversleeping, and overeating.
- Symptoms are worse in the evening and it often appears earlier in life, potentially linked to trauma.