Join Philip Gold, a leading researcher of depressive illness and author of 'Breaking Through Depression', alongside Güneş Taylor, a science communicator at The Francis Crick Institute. They dissect the complexities of depression, comparing melancholic and atypical forms, and delve into the effects of early trauma. Their discussion introduces innovative treatment approaches, including SSRIs and psychedelics, advocating for a personalized and holistic perspective on mental health that challenges traditional views.