
Mayo Clinic Talks The Risks and Benefits of Alcohol
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Jan 6, 2026 Warren G. Thompson, an internist and preventive medicine specialist at the Mayo Clinic, dives into the complex world of alcohol consumption. He explores common misconceptions about drink sizes and the real health benefits that might apply to those over 40. The discussion highlights the blurry line between moderate drinking and health risks, including cardiovascular issues and increased cancer risks. Thompson also warns against using alcohol for mental health relief and stresses tailored advice for different age groups. Practical takeaways include keeping to one drink a day with food.
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Measure What A 'Drink' Actually Is
- Measure alcohol amounts because people consistently underestimate drink sizes.
- Use standard measures: 1.5 oz 80-proof, 1 oz 100-proof, ~4.5 oz wine, 12–16 oz beer.
Patient Miscounts Strong Spirits As Few Drinks
- A patient reported 'two drinks a day' while actually consuming three ounces of 100-proof bourbon per drink.
- That habit meant he was actually drinking the equivalent of six standard drinks daily.
Debate Over Small Amounts' Net Benefit
- Evidence on alcohol's health effects is contested, with some experts saying zero is safest.
- Most data suggest small cardiovascular benefits for middle-aged and older adults, but not for those under 40.
