Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

BONUS: Bio-individuality and Fasting: Personalized Approaches to Metabolic Health with Dr. Jason Fung

Dec 29, 2025
Guest
Jason Fung
Dr. Jason Fung, a nephrologist and co-founder of The Fasting Method, dives into metabolic health and fasting strategies. He critiques the simplistic calorie-in/calorie-out approach, emphasizing hormonal influences on hunger. Dr. Fung discusses the impacts of food industry funding on nutrition guidelines and the unique metabolic challenges faced by midlife women. He shares insights on the benefits of fasting, the issues with GLP-1 drugs, and practical supplement recommendations for optimal health.
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INSIGHT

Hormones Drive Calories Not Vice Versa

  • Calories matter less than the hormonal drivers that control hunger and storage, especially insulin.
  • Targeting hormones (fasting, low-carb) addresses root causes rather than shallow "calories in, calories out."
INSIGHT

Foods Trigger Different Hormonal Responses

  • Different macronutrients trigger distinct satiety hormones like peptide YY and cholecystokinin.
  • Thus 100 calories of soda and 100 calories of eggs produce very different physiological responses.
ANECDOTE

Kempner Rice Diet Example

  • The Kempner rice diet (white rice and sugar) caused weight loss but was unbearably boring and unsustainable.
  • Fung uses it to illustrate that calorie-only arguments ignore pleasure-driven eating dynamics.
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