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ACR Journals On Air

Immunology for the Rheumatologist: Type I Interferon & Skin Disease

Dec 10, 2024
Dr. Victoria Werth, Chief of Dermatology at the VA Medical Center and Professor at the University of Pennsylvania, sheds light on the role of Type I interferons in autoimmune skin diseases like cutaneous lupus and dermatomyositis. She discusses the inflammation mechanisms and skin manifestations linked to these conditions, highlighting the challenges of misdiagnosis. Dr. Werth also explores advancements in immunotherapy, the personalized use of hydroxychloroquine, and the importance of collaboration in improving lupus treatment outcomes.
48:37

Episode guests

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Quick takeaways

  • Dr. Victoria Werth highlights the critical role of Type I interferons in driving inflammation and skin damage in autoimmune diseases like cutaneous lupus and dermatomyositis.
  • Emerging therapies targeting interferon pathways are showing promise for more personalized and effective treatment options in managing autoimmune skin conditions.

Deep dives

Season Wrap-Up and Future Prospects

The conclusion of the second season highlights the appreciation for audience engagement, with plans already underway for a third season. The upcoming season will start on January 21, 2025, promising a fresh look into complex autoimmune topics. The episode features an in-depth discussion with Dr. Vicky Worth, who focuses on the role of interferon in the skin, reflecting current advancements in autoimmune research. Listeners are encouraged to anticipate future episodes, which will delve into integrating autoimmune diseases with cardiovascular health.

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