The Optispan Podcast with Matt Kaeberlein

GLP-1 Agonists Could Delay Aging? Scientist Weighs-In | 74

13 snips
Oct 22, 2024
Discover the potential of GLP-1 agonists beyond mere weight loss, as they may play a role in delaying biological aging. Delve into the complex relationship between health improvements and aging processes. Explore how these medications could extend lifespan and healthspan, while examining the risks associated with caloric restriction. Learn about the importance of lifestyle changes alongside GLP-1 agonists, including nutrition and resistance training, to maximize their benefits and ensure better metabolic health.
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INSIGHT

GLP-1 Effects On Aging Diseases

  • GLP-1 agonists reduce appetite, prevent diabetes, reverse obesity, and lower risk of heart disease and stroke.
  • Weight loss from these drugs in obese people leads to reduced risk of multiple age-related diseases naturally.
INSIGHT

Metabolic Dysfunction Accelerates Aging

  • Obesity and diabetes accelerate biological aging, raising risk of age-related diseases.
  • GLP-1 drugs likely slow aging by reversing metabolic dysfunction in obese, high-risk individuals.
INSIGHT

Health Vs Biological Aging

  • Health improvement and slowing biological aging are correlated but not identical concepts.
  • Affecting some aging mechanisms may improve health without fully reversing biological aging.
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