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Ever Forward Radio with Chase Chewning

EFR 832: Cellular Fragility Syndrome - Newly Discovered Cause of Insulin Resistance, Type 2 Diabetes, Fatty Liver Disease and Aging with Dr. Stephanie Venn-Watson

Sep 10, 2024
Dr. Stephanie Venn-Watson, a veterinary epidemiologist, shares groundbreaking insights on the essential fatty acid C15:0 and its role in health. She introduces the concept of Cellular Fragility Syndrome, revealing how its deficiency can lead to accelerated aging and various diseases like type 2 diabetes. The discussion also highlights the revolutionary potential of C15 in promoting longevity and mitochondrial health. Dr. Venn-Watson emphasizes findings from dolphin research and the crucial distinction between natural and synthetic sources of C15 for optimal health.
01:03:09

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Quick takeaways

  • C15:0, an essential fatty acid, is crucial for cell membrane stability and plays a significant role in preventing cellular fragility syndrome.
  • A deficiency in C15:0 can lead to accelerated aging and serious metabolic issues like type 2 diabetes and liver disease.

Deep dives

Understanding C15 Deficiency

C15 is identified as an essential odd-chain saturated fatty acid that stabilizes cell membranes. Most people are unaware of its significance, though one in three individuals currently experiences a deficiency. This deficiency leads to 'cellular fragility syndrome', characterized by decreased resilience of cells, ultimately resulting in accelerated aging. The essential nature of C15 implies it must be obtained from the diet, as the body does not produce it naturally.

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