310: How to Biohack Our Cells to Reverse Aging with Dr. Greg Kelly
Apr 24, 2024
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Dr. Greg Kelly, a Naturopathic Physician, discusses biohacking to reverse aging at a cellular level, focusing on senolytics. They talk about health investments, improving quality of life, and using supplements like quercetin to target 'zombie cells'. The episode explores skepticism towards health trends, specialized multivitamins, and optimizing health through senolytics for various age groups.
Senolytics help combat aging by pruning senescent cells, promoting healthier cell turnover.
Qualia Senolytic shows improvements in joint symptoms, energy levels, and emotional well-being.
Lifestyle choices impact accumulation of senescent cells; combining senolytics with healthy habits can enhance efficacy.
Deep dives
Understanding Cellular Senescence and Senolytic Cells
Senolytic cells have been a focus of research as they play a crucial role in combating negative aging symptoms. Factors like stress contribute to cellular senescence, where cells resist apoptosis and linger in tissues. Senolytics are compounds that help prune away these lingering senescent cells, promoting healthier cell turnover. These cells impact various areas, including joints, energy levels, and emotional well-being, showcasing their significance in addressing aging concerns.
The Impact of Senolytic Cells on Joint Health and Overall Well-Being
Studies have demonstrated significant improvements in joint symptoms, energy levels, and emotional well-being with the use of senolytic compounds like Qualia Senolytic. Participants experienced a reduction in joint discomfort and stiffness, along with enhancements in energy levels and moods. The research highlights the potential benefits of senolytics in addressing key aspects of physical and emotional health impacted by aging.
Lifestyle Factors and Senescent Cell Management
While senolytics play a vital role in combating cellular senescence, lifestyle choices can also impact the accumulation and management of senescent cells. Factors like exercise and caloric restriction can help slow down the process, while stress and harmful habits may accelerate it. Incorporating senolytic compounds intermittently along with healthy lifestyle practices can enhance the efficacy of senescent cell management.
Balancing Hit-and-Run Dosing with Senolytics
Senolytics are typically administered through hit-and-run dosing, where compounds are taken intermittently to promote cell turnover effectively. The dosing regimen aims to prune away senescent cells without causing significant side effects. The approach balances the benefits of senolytics with the body's natural processes, providing a manageable and beneficial method for addressing cellular senescence.
Enhancing Brain Health and Cognitive Function with Senolytics
Senolytics show promise in supporting brain health and cognitive function, particularly in addressing inflammation and cellular stress that impact brain function. Research suggests that senolytics may play a role in improving brain fog, memory, and overall cognitive performance. By targeting cellular senescence, these compounds offer potential benefits for brain health and mental clarity as individuals age.
Gregory Kelly is the VP of Product Development at Neurohacker Collective, naturopathic physician (N.D.), and author of the book Shape Shift. He was the editor of the journal Alternative Medicine Review and has been an instructor at the University of Bridgeport in the College of Naturopathic Medicine, where he taught classes in Advanced Clinical Nutrition, Counseling Skills, and Doctor-Patient Relationships. Dr. Kelly has published hundreds of articles on natural medicine and nutrition, contributed three chapters to the Textbook of Natural Medicine, and has more than 30 journal articles indexed on Pubmed. His areas of expertise include nootropics, anti-aging and regenerative medicine, weight management, sleep and the chronobiology of performance and health.
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This episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct, or indirect financial interest in products, or services referred to in this episode.
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