The Human Upgrade with Dave Asprey cover image

The Human Upgrade with Dave Asprey

How Dogs Are Going to Make You Live Longer: Rapamycin & Longevity – Matt Kaeberlein : 1145

Mar 19, 2024
Explore how dogs and humans can enhance longevity with diet, stem cell therapy breakthroughs, and rapamycin trials. Learn about the correlation between diet and health span, the impact of rapamycin on aging, and the role of AI in data analysis. Discover the innovative use of retinal scans, webcam tech, and the worm bot in longevity research.
01:22:09

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Quick takeaways

  • Rapamycin shows promise in extending lifespan and improving health span in dogs and humans.
  • Personal experiences with rapamycin highlight its potential in reducing inflammation and enhancing quality of life.

Deep dives

Rapamycin and Its Effects on Lifespan in Dogs

Rapamycin, a molecule discovered on Easter Island, has shown potential in extending lifespan and improving health span in laboratory animals. Clinical trials in dogs have shown no adverse events at tested doses and have indicated improvements in age-related heart function and reported activity levels. The Triad trial, designed to detect a 9% change in lifespan, targets big dogs aging rapidly to ensure adequate statistical power.

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