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ImmunoTea: Your Immunology Podcast
ImmunoTea Episode 14 - B Cells and their Role in Inborn Errors of Immunity
Feb 19, 2024
Professor Stuart Tangye discusses the vital role of B cells in immune responses, focusing on antibody production and memory cell formation. The podcast also explores the interplay of immunodeficiency and autoimmunity, therapeutic targets for improving immunity, and the significance of B cells and antibodies in SARS-CoV-2 infection. Additionally, it delves into the diversity and functions of CD21 low or TBAP expressing B cells in the context of inborn errors of immunity.
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Quick takeaways
- B cells are essential in fighting infections by producing antibodies that neutralize pathogens.
- Inborn errors of immunity can disrupt B cell differentiation, leading to immunodeficiencies or autoimmune diseases.
Deep dives
Understanding the Role of B Cells in Immune System Protection
B cells are fundamental in the immune system's protection against infections. These blood cells produce antibodies that bind to and neutralize bacteria and viruses, clearing pathogens from the body. B cells can differentiate into plasma cells, which produce antibodies long-term, and memory B cells, providing rapid and enhanced immune responses upon re-exposure to pathogens.
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Discover
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