The Lifelong Journey of B Cells

This chapter explores the continuous journey of B cells from bone marrow formation to antigen scanning throughout the body, emphasizing the molecular changes and clonal expansion they undergo. It discusses the vital role of B cells in immune responses, particularly in antibody production and memory cell formation, highlighting their collaboration with T cells. Additionally, the chapter delves into the implications of inborn errors of immunity, historic cases of immunodeficiency diseases, and the significance of studying rare genetic disorders for understanding immune regulation.