BETTER! with Dr. Stephanie Estima | Strength, Body Composition & Perimenopause

Perimenopause Doesn't Cause ADHD, It Unmasks It: Reclaim Your Brain with Dr. Jolene Brighten

Oct 5, 2026
Dr. Jolene Brighten, a naturopathic endocrinologist and women’s health expert, explores why ADHD often goes unnoticed in women until midlife. They discuss masking through perfectionism, executive dysfunction, hormonal vulnerability windows, PMDD, perimenopause, genetics, nutrition, exercise, sleep, and supplements. A fascinating look at reclaiming focus when familiar strategies stop working.
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INSIGHT

Why The Menstrual Cycle Amplifies ADHD

  • Estrogen supports dopamine, norepinephrine, acetylcholine, serotonin, mitochondrial function, and brain energy.
  • As progesterone dominates the luteal phase, ADHD symptoms, fatigue, impulsivity, and follow-through problems can intensify.
INSIGHT

The Five Hormonal Pressure Points

  • ADHD symptoms can worsen during five hormonal transitions: puberty, pregnancy and postpartum, perimenopause, postmenopause, and premenstruation.
  • Progesterone sensitivity may reflect abnormal GABA responses or rapid neurosteroid metabolism.
ADVICE

ADHD Involves Brain Energy Systems

  • ADHD brains may struggle with glucose metabolism, mitochondrial function, oxidative stress, and neuroinflammation.
  • Medication decisions require clinical guidance because stimulant effects may differ dramatically between ADHD and non-ADHD brains.
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