Progesterone Sensitivity and Hormone Therapy

Dr. Jolene Brighten explains why ADHD in women is so often missed, misdiagnosed, or dismissed as personality. She covers the five hormonal life stages that make ADHD symptoms worse, why perimenopause "unmasks" ADHD rather than causing it, and the food and exercise protocols that actually support an ADHD brain.

Get Dr. Brighten’s Book, ADHD & Women: https://drbrighten.com/adhd-and-women/

🎤 TOPICS COVERED

• ADHD in women: symptoms, diagnosis, and why it's missed for decades
• Why ADHD looks different in women versus men
• Perimenopause and ADHD: why symptoms get worse in midlife
• The five hormonal stages that worsen ADHD (puberty, pregnancy/postpartum, perimenopause, postmenopause, premenstrual phase)
• Executive dysfunction explained: time blindness, task paralysis, and emotional dysregulation
• ADHD masking in women: people-pleasing, perfectionism, and burnout
• Estrogen, progesterone, and the ADHD brain: how hormones affect dopamine and focus
• PMDD and ADHD: the connection between your cycle and your symptoms
• Progesterone sensitivity and hormone replacement therapy for ADHD women
• PCOS, PMOS, and the androgen-ADHD connection
• ADHD and genetics: is ADHD hereditary
• Nutrition for ADHD: gut health, protein, and the three foods Dr. Brighten recommends weekly
• Exercise and the ADHD brain: lactate, BDNF, and why movement improves focus
• Best workouts for ADHD: strength training, sprints, and mobility work
• Creatine, saffron, bacopa, and other supplements for ADHD
• Sleep and ADHD: delayed sleep phase syndrome and the default mode network
• Late-diagnosed ADHD in women: why so many women are diagnosed in their late 30s and 40s

📎 RESOURCES MENTIONED

• Number of ADHD Patients Rising, Especially Among Women - https://www.epicresearch.org/articles/number-of-adhd-patients-rising-especially-among-women/
• ADHD link to severe premenstrual disorder uncovered in women - https://www.qmul.ac.uk/news/latest-news/2025/science-and-engineering/se/adhd-link-to-severe-premenstrual-disorder-uncovered-in-women.html
• Genetics of attention deficit hyperactivity disorder - https://pmc.ncbi.nlm.nih.gov/articles/PMC6477889/
• Crocus sativus L. Versus Methylphenidate in Treatment of Children with Attention-Deficit/Hyperactivity Disorder: A Randomized, Double-Blind Pilot Study - https://pubmed.ncbi.nlm.nih.gov/30741567/
• Moderate Exercise Tied to Improved ADHD Symptoms in Young Men - https://www.patientcareonline.com/view/moderate-exercise-tied-improved-adhd-symptoms-young-men
• Adult attention-deficit hyperactivity disorder and clinical correlates of delayed sleep phase disorder - https://www.sciencedirect.com/science/article/abs/pii/S0165178119324564
• Methylphenidate and Its Impact on Redox Balance and Behavior - https://pmc.ncbi.nlm.nih.gov/articles/PMC12565610/
• Creatine Promotes Endometriosis by Inducing Ferroptosis Resistance via Suppression of PrP - https://pmc.ncbi.nlm.nih.gov/articles/PMC11481182/
• Website: https://drbrighten.com
• Instagram: https://www.instagram.com/drjolenebrighten
• YouTube: https://www.youtube.com/@DrJoleneBrighten
• Tiktok: https://www.tiktok.com/@drjolenebrighten

BIO
Dr. Jolene Brighten is an internationally recognized expert in hormones, women’s health, and ADHD across the female lifespan. A board-certified naturopathic endocrinologist, nutrition scientist, certified menopause specialist, and sex counsellor, she is widely known for translating complex hormonal science into clear, clinically relevant care for patients and the doctors who treat them. She is the bestselling author of Beyond the Pill and Is This Normal, and is the host of The Dr. Brighten Show, a top-rated women’s health podcast. More at drbrighten.com

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