Nutrition Facts with Dr. Greger Suppressing mTOR
18 snips
May 29, 2025 Discover the intriguing role of mTOR as a key player in aging and longevity. Delve into how inhibiting this enzyme with rapamycin could be the next breakthrough in anti-aging treatments. Learn about its promising effects on immune function, particularly in older adults, and how it might enhance rather than suppress immune responses. The discussion also touches on the importance of safe practices and nutrition in achieving health transformation.
AI Snips
Chapters
Books
Transcript
Episode notes
mTOR: Aging's Engine
- mTOR is a master regulator of growth and a key modulator of aging, essentially the engine of aging in adulthood.
- It drives cell growth and proliferation but lacks brakes, causing aging to accelerate after reproductive age.
mTOR Suppresses Cellular Cleanup
- The mTOR pathway fosters growth while suppressing autophagy, halting cellular cleaning and rejuvenation.
- This uncontrolled growth speeds up aging, but suppressing mTOR can slow aging and extend lifespan.
Rapamycin Extends Lifespan Universally
- Rapamycin, derived from Easter Island bacteria, inhibits mTOR and extends lifespan universally across tested animals.
- It works even when administered starting in midlife, showing powerful anti-aging properties without being species-specific.
