Dr. Baraki and Dr. Feigenbaum discuss research papers on artificial sweeteners' impact on health, anabolic steroid use, and plastics' effects on cardiovascular health. They also touch on topics like managing atrial fibrillation during training and the challenges of plastic exposure in food.
Consuming over two liters of artificially sweetened beverages per week may increase atrial fibrillation risk, but genetic risk plays a significant role.
Anabolic steroid users face a higher risk of all-cause mortality, attributed to factors like polypharmacy and pre-existing diseases impacting study results.
Healthcare professionals encounter challenges in monitoring anabolic steroid users for side effects due to lack of research and stigma surrounding high-dose steroid use.
Deep dives
Atrial Fibrillation Risk Associated with Artificially Sweetened Beverages
Consumption of artificially sweetened beverages was studied for its potential link to atrial fibrillation risk. The study found no increased risk with consumption less than one or one to two liters per week, but a 20% higher risk for those consuming greater than two liters per week. However, the genetic risk for atrial fibrillation greatly outweighed the impact of artificially sweetened beverages on risk.
Anabolic Steroid Use and Mortality
A study investigated mortality rates among users of anabolic steroids compared to a control group over a follow-up period of 11 years. Results showed a 181% increased risk of all-cause mortality in the steroid user group. However, the absolute risk of death was low in both groups. Factors like polypharmacy, unknown doses, potential contamination, and pre-existing diseases were pointed out as confounders impacting the results.
Challenges in Monitoring Anabolic Steroid Use
Monitoring anabolic steroid users for side effects or health conditions is challenging due to stigma, lack of research, and difficulty in obtaining clear dosing information. This poses a significant barrier for healthcare professionals who may need to provide guidance on monitoring and managing potential risks associated with high-dose steroid use.
Complexity of Health Risks and Education on Anabolic Steroid Use
The complexity of health risks associated with high-dose anabolic steroid use highlights the need for more research and education in monitoring and managing potential side effects. Healthcare professionals face challenges in providing tailored guidance due to limited resources and information in this area.
Discussion on Steroid Usage and Risks
Steroid consultation involves understanding each individual's goals and level of commitment to using steroids. The podcast highlights the complexity of predicting harm from steroid use, especially in young individuals. The conversation emphasizes the challenges in determining the risks associated with short-term anabolic exposure and underscores the importance of remaining humble and skeptical in science communication regarding performance-enhancing drug use.
Exploring Plastics Exposure and Cardiovascular Effects
The podcast delves into the presence of micro and nano plastics in atheromas and their potential link to cardiovascular events. A study on carotid artery stenosis patients reveals detectable plastic particles in a significant portion of plaque specimens. Individuals with plastic in their plaques tended to be younger, male, and have underlying health conditions like diabetes and cardiovascular disease. While the study suggests an increased risk of heart attacks, strokes, or death in those with plastic particles, the wide confidence interval highlights uncertainty and the need for further research on the health implications of plastics exposure.
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