Brain Aging & Alzheimer’s Prevention: The Future of Cognitive Health Testing | Dr. Christin Glorioso | 106

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Dr. Matt Kaeberlein & Dr. Christin Glorioso, founder of NeuroAge Therapeutics, explore groundbreaking advancements in brain aging and Alzheimer's prevention. Learn how cutting-edge brain age testing—combining MRI, cognitive assessments, blood biomarkers, and genetics—can predict Alzheimer’s risk decades in advance. Discover the impact of lifestyle factors like diet, exercise, and sleep on cognitive decline, plus the latest in medications, including GLP-1 agonists and hormone replacement therapy.

0:00 - Introduction to NeuroAge & Brain Aging2:50 - Understanding the Brain Age Clock & Alzheimer's Risk6:30 - The Role of Genetics in Brain Aging10:15 - How MRI Scans Measure Brain Health14:40 - Cognitive Testing & Neuro Games Explained19:10 - The Impact of Lifestyle on Brain Aging24:55 - Medications & New Alzheimer’s Treatments29:40 - The Potential of GLP-1 Agonists & Hormone Therapy36:15 - Challenges of Direct-to-Consumer Brain Age Testing48:30 - Final Thoughts on Cognitive Health & Future Research

Producers: Tara Mei, Nicholas ArapisVideo Editor: Jacob Keliikoa

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Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.

On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!