Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition Human Performance Scientist: Are GLP-1 weight loss drugs a solution or a risk? | Andy Galpin
Jan 9, 2026
In this discussion, guest Andy Galpin, a human performance scientist specializing in metabolism, tackles the pros and cons of GLP-1 weight loss drugs. He shares insights on their effectiveness and the importance of understanding potential side effects like muscle loss. Andy emphasizes that while GLP-1 drugs could revolutionize weight loss, they shouldn’t be seen as a standalone solution. He advocates for a holistic approach, combining medication with nutrition education and strength training to achieve lasting health benefits.
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GLP-1s Are A Game Changer
- GLP-1 drugs are the most significant weight-loss development we've seen and may save millions of lives.
- Andy Galpin argues they outperform any diet or supplement historically despite unknowns and trade-offs.
Promise Comes With Real Unknowns
- The drugs have clear holes: side effects, inappropriate use, and lack of long-term data.
- Andy Galpin stresses we must acknowledge these risks even while accepting the drugs' promise.
The Plumber Example
- Imagine a 38-year-old plumber with 70 kilos to lose; modest muscle loss is acceptable if the drug prevents early death.
- Andy Galpin uses this example to highlight trade-offs between imperfect treatment and survival.