
Rheumnow Podcast
TNR - Methotrexate Decisions
Sep 20, 2023
Dr. Michael Weinblatt is a renowned rheumatology expert, accompanied by Grace Wright, a physician skilled in autoimmune diseases, Richard Conway, a treatment methodology authority, and Joel Kremer, a specialist in rheumatic conditions. They delve into the intricacies of methotrexate as a treatment option. Topics include the critical balance of folate supplementation, managing liver health, and the impacts of alcohol on treatment. They also discuss methotrexate's role alongside vaccinations and its use in patients with interstitial lung disease, emphasizing the necessity of careful monitoring and personalized treatment strategies.
58:15
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Quick takeaways
- Methotrexate remains an essential initial therapy for rheumatoid arthritis, highlighting its ongoing relevance despite newer treatment options.
- Folate supplementation is crucial in managing methotrexate's side effects, with daily dosing recommended for optimal patient outcomes.
Deep dives
Methotrexate as a Cornerstone Therapy
Methotrexate remains the primary initial therapy for rheumatoid arthritis (RA), emphasizing its importance in treatment protocols across the globe. Many rheumatologists agree that in the coming decade, methotrexate will continue to be a focal point in RA management. Discussions among experts highlighted that despite the introduction of newer therapies, methotrexate still provides significant benefits. This consensus is shaped by extensive experience with the drug and ongoing research supporting its efficacy in managing RA.
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